Systemic cure for systemic disease.

 Very enjoying reading vestnik, waiting every issue. Am interesting through vestnik receiving advices by dermatologist about a cure for my disease is sclerodermatitis, but medic calling her sclerodermia or systemic atherosclerosis ,and cures her as autoimmune disease, but just rheumatologists.Thus, for answer to your question, we asked vestnik  correspondent Kifurjak to address doctor-rheumatologist Potanin.

And am wondering in such old diagnosis, maybe local doctors shared to her, she must not though about it, and am worry  ,that cure prescribing is not adequate. A  scleroderma  is serious autoimmune disease as origin too, when organism trying destroying , kill an own tissues or organs.And,   kinds of scleroderma are much, but base spreading are nidus and systemic, first is am sure in our reader, that by diagnosis is a risk for cosmetic defects,  she  is   transferring  in systemic form, sometimes, but its dangerous disease.

1. A how displaying nidus scleroderma?

As on a skin displaying are niduses with plaques, on begin is oedema, after hardening, skin stopping taking in wrinkle. She is after atrophying, elasticity destroying, and skin sensitiveness, which hard by touching. Niduses are different forms and sizes, and displaying on any body parts.

2. And here kind is simple fight.

Not true, a long, systematic  cure needing, begin with corticosteroid ointments as CelestodermB WITH Garamicine or  Ichtyolum ointment, they  are restoring vessels, fighting inflammation, in mobility joints increasing prescribing injections for niduses of damages with lidaza, are remedies softening damage skin. A good recommended ointments with calcipotriol are dayvonex, psorcutan, and effectivity they are with PUVA therapy a special ultraviolet radiation for damage places. And afecting on recovering and using one forms of vitamin D is rocaltrol, osteotriol on 0.25-0.5 mg  in a day.

3.Lets talk about a systemic scleroderma, which  is affecting on health more.

 Yes, its dangerous disease, and women's affecting on 7 times more,than males, reasons are bot kinds are not known , immunity is failure,and beginning attacking organs and tissues as foreign and trying theirs rejecting. As in last case, a disease beginning with skin damage, which is sclerotizing, hardening as on a finger of hands and face, when a skin, like pulling up around mouth, and mouth stopping full opening. In developing a disease, these changes transferring on a skin of all body. And am shared before, but fingers are dryness, contractures adding, and hurt, like in arthritis and not bending out. In a nail bed, and pillows of fingers are bladders having, like pimples, after transferring till ulcers. Thus,  in rheumatologists rules, if patients complaining on an  ache hands, thus a need to check his a full. And attached by plasters too, attached on fingers and after scars forming, needing paying attention on serous disease. A not rare Raunaud s syndrome having, fingers are sharply reacting on a lowering temperature, as they are hurt,after cyanosis having, after  a redness, such tricolour variant, and with ache, and numbness having.

4. Depressing picture, but external damages here are not dangerous..

No, its a not true, organs involving also, a beginning with a most harmless  is gullet damage with heartburn, in swallowing feeling lump, as in external damages needing adding gastroscopy testing, and x-ray testing for gullet, which is in scleroderma is balloon narrowing to below, as in other gullet damaging this is not having. A very hard in sclerodermas are lungs destroying, with dyspnoe, breathe hard and failure, dried cough, and these symptoms we can to write-off on an anything, but in scleroderma connective tissues  of lungs affecting as a skin of a body , that shows just magnet resonance tomography. But if skin not changing, but heart is problems having, and lungs, kidneys, etc , a scleroderma is not must be. Thus, with conservative researches for organs, a common analysis for this disease is capillaroscopy for nail bed at haematologic cabinets. A small gadget will show capillaries conditions and showing variant by which disease will display and  select right scheme curing.And for diagnosis right using other methods as immunologic blood tests, skin biopsy.

5. A time to talk about a cure.

A disease multifactorial ,and three mechanisms are having on which needing affecting.

First group preparations affecting on vessels tone and blood coagulation. Second is on a reason ,which given a failure for immunity, third is to prevent for development of sclerotic displays on the skin.

And for widening vessels use antagonists groups of calcium preparations as nifedipine, amlodipine as on big dosages, but its a not good of side effects, if patients having hypertension, but other variants are not having.

Also needing using enap, prestarium, fosicard by select, and on maximal dose,but these remedies are saving damaged kidney, that before are could not. As for increasing blood fluidity  use by select from 1/4 pill of aspirin til thrombo ACC, curantyl on 225-250 mg/day, trental on 800-1600 mg/day, and not rare prescribing other remedies in combination , as they are affecting on the early mechanisms for blood fluidity.  And define a concrete mechanisation is must your doctor in depending on from disease development. And a how to affect on immune system, begin from corticosteroids, they are using not always and on not significant doses on 15-20 mg of prednisolone/day, and just in hard damaging kidneys and lungs are increasing on 60-80 mg/day, and in such cases needing cytotoxic as cyclophosphamide.

And for preventing damaging for connective tissue of skin, and other organs am prescribing cuprenil, begin with big dosages on 1 mg/day, after decreasing on 400 mg/day, a not harmful remedy, but need a regular doing blood tests and urine.

 About remedies affecting on skin am shared before. Avoiding over cooling, gloves on winter change on warm mittens, avoid to sun bath on a sun, avoid to lift heavy items and bag in women's not keep in hands, but wear on elbow. Am offered are three directions in cure, but other too having variants in depending on from a level disease development. And modern remedies here are expensive, but on any case cure is hard, and results are possible in complex therapy. Unfortunately exit is not having, its dangerous disease, and good fighting his a not just need prescribed right cure, but a discipline by patient.