On cold beginning are many patients doctor visiting with complaints on the different ache symptoms ,which are displaying after leaving home, usually allergists will work with these patients, where diagnosis put is cold allergy. In a one these allergy reactions having on minus 24-28C, and higher, in other on minus 8-10C and lower. And in a few after cold washing, as right away or a few minutes later are feeling burning, distension in face, bubbles rashes, itch, angioneurotic edemas, cough, hard breathing. Cold is a not allergen. Its an expansion mechanism for allergy development. Under affecting fat cells, finding in connection tissue are free biologic active substances, which causing a high penetrating of blood vessels, bronchus spasms, edema and other allergy displaying. And in low temperatures are changing antigen effects of proteins, in result of which forming autoantigenes, on which organism reacts are autoantibodies forming. And of these process and staying itching displaying, bubbles rashes, edema, bronchus spasms, allergy rhinitis and conjunctivitis. And of cold allergy suffering peoples, which in organism having chronic nidus infections as caries, tonsillitis, gingivitis, cholecystitis, pyelonephritis and other diseases . Doctors are having effective methods for diagnosis and cure.

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