In the top left corner a black oval means a chromosome carryng a mutation, and light oval is normal chromosome a same pair, but on the scheme showed one pair for chromosomes, other chromosomes are normal. In the forming for sex cells in patient chromosomes every pair as discrepancy, thus half of sex cells having chromosome with mutation, half is normal. And on our scheme showed variant for born in a one from spouses are two sicked/A, B, and two healthy C,D childrens.
As showed on the scheme two, half of sex cells by both parents carries mutation, half of theirs are normal, and not ability advance to predict a which sex cells enter in fertillization proces .Are possible four variants.
In a first entering for fertillization are sex cells, carry mutation and thus children will born a sick/A/, in second and third cases/B and C/ embryo developming from a one healthy cell, a one by carry mutation, thus childrens will be a such hide carries, as theirs parents. And on the fourth case /G/, DEVELOPMENT EBRYO HAVING NORMAL CHROMOSOMES, thus baby will healthy . But his offspring will be a healthy, mutation self dissapears. By scheme probably ,that baby borned will sick will be theoreticaly on 25 percents. Carries are genes of recessive disease will transfer from generation in generation, nothing displaying, but till you are marry with a same gene carry and till in fertillization will enter sex cells, carry mutation. But its a not often happening, thus about a family doomed families with genetical diseases is need to recognize as mistake. In genetical diseases suffering is ability was born a healthy baby,which will be had a normal offspring. But not hope on case, that all,what we are shared about a possible displaying pathologic genetic is just not hope for parents, but to convince theirs in needing for genetical-medical consultation, that specialist advise will dispel all worries, or prevent from a irreparable mistake, why a need to risk?
B , C ARE В -Г.
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