A main trick are infection complications.

 On my 54 y.old are 5 years having rheumatoid arthritis. And with hands, wrists  are destroying knee and hip joints. And used methotrexate, half year a used prednisolone, but situation worsened, that am not mobility.A next stage for cure a hard artillery as biologic remedies, doctor gives me a hope, that they are will help, but what is to say specialist from zoz press.

Biologic anti-inflammatory remedies are fast-growing groups for modern preparations are fighting rheumatic diseases answers Rheumatologist Smitienko. They are calling gene-engineering preparations GEP as Remiceid, Enbrel, Humira, Orensia, Eiflera, Tals, Ilaris ARE using for rheumatoid arthritis curing, ankyloses spondylitis , psoriatic arthritis, acute gout attacks. And data substances a big protein structures, which are getting in process for hard and long manufacturing, they are receiving hard , and affecting on a high cost. Biologic preparations having two forms as infusion as dropsy, and subcutaneously introducing, they are selectivity, pointy affecting on immune system chains, blocking inflammation substances.But also on a good effectivity they are having side effects, as risk for infection complications are on the first 6 months a cures, thus are doctors advising doing vaccinations everyday against flu, and not depending on epidemic attack, and one for 5 years against pneumococcus infections, hepatitis B, IF you are never vaccinated and sicked  from his. And before a start using biologic therapy need to exclude  a hide tuberculosis infection , thus to do x-ray test or CT  for lungs and use a one method for tuberculosis diagnosis as Test Mantoux, after every 6-12 months doing test such, and also you need to test on AIDS, Hepatitis B, C, syphilis.And take patience, a cure with biologic remedies and synthetic basis are anti inflammation keeping for many years. And doctor's ability to combine a biologic and synthetic preparations, but never prescribing are both on the same time. That is leading to serious complications is immunity oppression.