Second circulation canalization includes in itsels are heart,arteries, veins, blood capillaries, lymphatic nodules,

 lymphatic stems,and capillaries.And theirs brunching canalization is digestion as with mouth with saliva, forming with importance saliva glands, gullet, stomach, small bowel, as irrigating with gall, and juices of pancreas gland, thin bowel with a lots of villi, thick bowel with a power very muscle in anal duct.And remember any tight nourishing substance, entering in digestive highway, transforming in solution, in liquid. And therefore, organism is a system of canals and tubules, in which non-stopping gas and liquids. And with a big life s inflow as with arteries and veins and close with lots of lakes small of blood and lymphatic capillaries are finding continents, as entering in ocean of extracellular liquids, are brain, lugs, heart, liver, muscle system, as  irrigating of countless vessel nets. All organs are heart, lungs, liver, spleen, kidneys, pancreas, bowel, diaphragm, sex organs,  bone marrow, acoustic apparatus, organ vision is 1/3 of mass a human s body.

And every quality, or quantity changing for liquids structures causing a hurt destroys.And if liquid structures, over loading with metabolites,as surviving a still attacking of new metabolites, thus life staying a not possible. And circulation blood size are 5l, lymph 2 l, and within a hour liver gets 100 l. of blood and 40 l. of lymph. Normal vertical diameter liver is 14 cm, spleen 7 cm.And if with a percutation help you are finding her diameter are 20-24 cm, spleen diameter 18-20 cm, and must admit,that blood lakes in liver and spleen delaying with all consequences for acidifying and feeding all organs. And spleen with liver are understand undergo  a hyper hydration, over filling are extracellular liquids.And you can to hypothesise/as to admit/are serous destroys in a big vessel  net of portal vein, as giving a normal composition a blood ubiquitous , and in all organs of peritoneum cavity.