Common remedies against diabetes.

 Metformin-Remedy for first line and a most prescribing remedy for decreasing insulin resistance in patients of 2 nd diabetes type and syndrome  PO/SPO/. Metformin improves sensitiveness to insulin, rising  activity for insulin receptors, increasing synthesis of glycogen, and attraction and activity of glucose transported GLUT4 .He  also affects on over esterification of free fatty acids and inhibits lipolysis, that later will improve sensitiveness to insulin for an account lowering for lipotoxicaly a fatty acid.

Glp-2 glucagone similar peptide 1 -id bowel hormone ,which increasing secretion insulin by glucose dependency method, activating receptors GLP1 ,staying in beta cells of pancreatic Iceland.

Agonists of receptors GLP1 ,including liraglutine, semaglutide, dulaglucid and exenatid today are approved for diabetes 2 nd type. These agonists  receptors GLP-1  are suppressing inflammatory reaction of macrophages,as lowering insulin resistance.And, remedies these groups also using for a cure other diseases as tied with insulin resistance to insulin, and obesity , for example SPO. In one of 12 week research for, liraglutid it founds too effectivity as metformin , in a cure for SPO. litaglutid, simaglutid and same remedies improving glucose homeostasis, rising an  early insulin answer on meal using and suppressing secretion for glucagon ,and suppressing appetite. Lowering weight, normalization index for insulin resistance HOMA-IR ,normalization tolerance to glucose and free level of testosterone in blood serum are other being positive effects of metformin, and preparations from agonists groups GLP-1. Researches are shown, that  cure for low dosages semaglutid, analogise for liraglutid of new generation, is lowering weight in 80 percents with obesity patients,SPO, are  which not reacted on latest methods by life correction ,and on many cases lead to menses normalized as cycle, and less side effects.

Inhibitors DPP-4  as gemigleptin, saxagleptin , sitagliptin, tenegliptin, trelagliptin, vildagliptin etc are using in all world since 2006 y, for diabetes 2 nd type cure and  improves sensitiveness to insulin. 

Inhibitors SLGT2 as  canagliflozin,dapagliflozin, and empaglifozin  affecting good on lowering insulin resistance in protection of function of beta cells of pancreas gland. 

Agonists PPAR-U tiasolidindiones as pioglitazon, or rosiglitazon using in diabetes, increasing accumulation of lipids  in adipocytes, decreasing ectopic lipids accumulation and improving sensitive to insulin in liver and skeleton muscles. But they are having limiting effectivity, bad enduring and serious side effects, including hypoglycaemia, increasing weight, fractures, vomiting. And today they are rare using.

And this book not claims on a comprehending describing reception remedies for diabetes 2nd type cure, thus am not detailed stopping on theirs. And also against diabetes are common remedies normalizing consequences of your bad mode of life ,as:

Anti cholesterol remedies, antihypertensive, anti-cancer, against gout, in significant rising level of urea acid, antidepressants, antianxiety, against dementia, against sterility .And , certainly these diseases having genetical predisposition, but affecting on theirs just 20 perc as 2-10 perc often, others are epigenetic, so as a how you are self affecting on displaying or suppressing  genetical risks of certain diseases by an own life mode, that on ending result forming your health or disease.

Any specialist are doctors using remedies for cure diabetes second type, but lots of are not known , what is to do if in patient having insulin resistance or pre-diabetes, individual standard advice  is lowering sweets in menu!