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Contents

Molecular Biology

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Vol. 58, No. 6, 2024

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REVIEWS

Antibiotic Resistance: Threats and Search for Solution

S. N. Kochetkov p. 971  abstract

History of the Creation of a New Generation of Antibiotics of the Group of Polycyclic Glycopeptides

E. N. Olsufyeva p. 980  abstract

Unveiling Neisseria gonorrhoeae Survival: Genetic Variability, Pathogenesis, and Antimicrobial Drug Resistance

B. L. Shaskolskiy, I. D. Kandinov, D. A. Gryadunov, and D. V. Kravtsov p. 1003  abstract

Enzymes of ADP-Heptose Biosynthesis As Targets for the Creation of Broad-Spectrum Antibacterial Drugs

T. A. Seregina, I. Yu. Petrushanko, K. V. Lobanov, R. S. Shakulov, and A. S. Mironov p. 1039  abstract

Distribution of Antibiotic Resistance Genes in Microbial Communities: The Impact of Anthropogenic Pollution

I. S. Sazykin, M. A. Sazykina, and A. R. Litsevich p. 1049  abstract

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PREPARATION AND STRUCTURAL–FUNCTIONAL ANALYSIS OF ANTIMICROBIAL AGENTS

Toxicity Study of the Pharmacological Pair of Encapsulated Citrobacter freundii C115H Methionine γ-Lyase/Methiin

S. V. Revtovich, V. V. Kulikova, V. S. Koval, A. D. Lyfenko, V. A. Kazakov, A. S. Chernov, G. B. Telegin, A. S. Zemskaya, N. V. Anufrieva, E. A. Morozova, and P. N. Solyev p. 1063  abstract

Synthesis and Antimicrobial Activity of Thiosulfinates and Allicin Analogues

V. M. Puchkov, A. D. Lyfenko, V. S. Koval, S. V. Revtovich, V. V. Kulikova, N. V. Anufrieva, A. S. Zemskaya, E. A. Morozova, and P. N. Solyev p. 1074  abstract

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PRODUCTION AND STRUCTURAL–FUNCTIONAL ANALYSIS OF ANTIMICROBIALS

Development of a New Inhibitor of Bacterial Cystathionine γ-Lyase Based on 6-Bromoindole and Aminothiophene

R. A. Novikov, D. N. Platonov, A. Yu. Belyy, K. V. Potapov, M. A. Novikov, Yu. V. Tomilov, O. I. Kechko, T. A. Seregina, P. N. Solyev, and V. A. Mitkevich p. 1082  abstract

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GENOMICS. TRANSCRIPTOMICS

Identification of the Clinical Isolate CCGC 19/16 as Bacillus cytotoxicus

N. B. Polyakov, D. S. Karpov, M. V. Zubasheva, A. N. Polyakova, D. N. Shcherbinin, A. I. Solovyev, M. V. Lavrentiev, T. A. Smirnova, M. A. Sukhina, and V. G. Zhukhovitsky p. 1089  abstract

Antibiotic Resistance Genes in Cattle Gut Microbiota: Influence of Housing Conditions

Sh. A. Begmatov, A. V. Beletsky, A. L. Rakitin, A. P. Lukina, L. O. Sokolyanskaya, A. V. Rakitin, L. B. Glukhova, A. V. Mardanov, O. V. Karnachuk, and N. V. Ravin p. 1101  abstract

Distribution of β-Lactamase-Producing Enterobacterales among Patients in Surgical and Therapeutic Departments of a Multidisciplinary Hospital

S. Yu. Meshchurova, A. G. Korobova, and L. M. Samokhodskaya p. 1111  abstract

CpG Traffic Lights Are Involved in Active DNA Demethylation

A. V. Lioznova, and Yu. A. Medvedeva p. 1122  abstract

Exploring Unique Sequence Repeat Patterns and Secondary Structures in rDNA Internal Transcribed Spacers ITS1 and ITS2 for Characterization of Catfish Species

M. Imran, and S. Nafees p. 1132  abstract

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METHODS

Surface-Enhanced Raman Scattering to Improve the Sensitivity of the MTT Assay

V. A. Mushenkov, D. A. Lukyanov, N. F. Meshcheryakova, V. I. Kukushkin, and E. G. Zavyalova p. 1148  abstract

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AGING AND GEROPROTECTIVE TECHNOLOGIES

Antiglycation Activity of Isoindole Derivatives and Its Prediction Using Frontier Molecular Orbital Energies

U. M. Ibragimova, N. V. Valuisky, S. A. Sorokina, X. I. Zhukova, V. R. Raiberg, and R. A. Litvinov p. 1157  abstract

New Epigenetic Markers of Age-Dependent Changes in the Cardiovascular System

L. M. Ermakova, E. A. Davydova, E. V. Kondakova, K. V. Kuchin, and M. V. Vedunova p. 1165  abstract

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REVIEWS

DNA Methylation Detection: Fluorescent and Colourimetric Methods Based on Methylation-Associated Restriction Endonucleases

Y.-Y. Xu, and L. Xiao p. 1178  abstract

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CELL MOLECULAR BIOLOGY

Silencing of the S-Phase Kinase-Associated Protein 2 Gene (SKP2) Inhibits Proliferation and Migration of Hepatocellular Carcinoma Cells

Y. Y. Zhao, Z. X. Gao, S. D. Wei, and W. Song p. 1197  abstract

Expression Profiles of TRIM Family Genes in Neuronal and Glial Cell Cultures of Healthy Donors and Patients with Parkinson’s Disease under Normal Conditions and Upon Neuroinflammation

V. V. Nenasheva, E. V. Novosadova, T. P. Gerasimova, L. V. Novosadova, A. Y. Kotok, E. L. Arsenieva, E. A. Stepanenko, I. A. Grivennikov, and V. Z. Tarantul p. 1208  abstract

Triosephosphate Isomerase Inhibition by Resveratrol: A New Mechanism of Anti-Glycolysis in Breast Cancer

G. Tuna, O. Akgün, and F. Arı p. 1219  abstract

Ras-Related Protein Rab-7a Regulates Glucose Metabolism under Hypoxia by Interacting with Hypoxia-Inducible Factor 1-Alpha in HepG2 Cells

Y. Y. Wang, J. Y. Zhang, X. L. Zhu, Y. Liu, and X. P. Wu p. 1230  abstract

Mechanism of Oxidative Stress Inducing Pyroptosis by Activating the NLRP3/Caspase-1/GSDMD Pathway in Lens Epithelial Cells under High Glucose Environment

C. L. Fang, L. M. Qian, and N. Ma p. 1241  abstract

Afamin Ameliorates Testosterone Propionate (TP)-Induced Oxidative Stress and Mitochondrial Damage in Human Ovarian Granulosa Tumor Cells (KGN) by Upregulating the Expression of SIRT1

Y. L. Ma, Z. W. Li, Z. Wang, and A. J. Yang p. 1250  abstract

Cytotoxic Effects of the Combination of Pam3CSK4 with Carfilzomib, Ixazomib, and Venetoclax in Human Multiple Myeloma Cells

K. Avci, M. Özdemir Erdoğan, S. H. Yildiz, and F. Yavaşoğlu p. 1268  abstract

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STRUCTURAL-FUNCTIONAL ANALYSIS OF BIOPOLYMERS AND THEIR COMPLEXES

N-Acetylgalactosamine-Conjugated Antisense Oligonucleotides Designed as Inhibitors of ABCB1: Coping with Multidrug Resistance in Hepatocellular Carcinoma

B. Hasturk, T. Avsar, S. Ozbas, B. Karademir Yilmaz, and F. Eren p. 1280  abstract

Elucidating the Effects of Aromatic Mutations on the RNA Binding Efficacy of CELF2 Protein

N. Kumari, N. Sarovar Bhavesh, and Y. Hasija p. 1293  abstract

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METHODS

Adapting Mouse Genome Editing Technique from Scratch Using in utero Electroporation

J. V. Popova, V. D. Bets, E. S. Omelina, L. V. Boldyreva, and E. N. Kozhevnikova p. 1312  abstract

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BIOINFORMATICS

Unraveling Cancer Progression in Oral Squamous Cell Carcinoma through Regulatory Network Analysis; miRNA-Target Gene Interaction

Y. Arianmehr, G. Nuoroozi, S. H. Tackallou, M. Peyman, S. Alihosseini, A. Atashi, M. Ajami, M. Ajami, H. M. M. Sadeghi, F. Yazdani, N. Yazdani, Z. Molavi, F. Mohebichamkhorami, S. A. Mirmotalebisohi, and H. Zali p. 1321  abstract

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Retraction Note

Retraction Note: Three Important Discoveries in the Field of the Cytoskeleton’s Proteins Functioning on the Drosophila melanogaster Model

Yu. E. Vorontsova, E. L. Zavoloka, R. O. Cherezov, and O. B. Simonova p. 1340  abstract