A cure is fast, for a not long sick.

 Natalja written to us, as in her hubby diagnosis is rheumatoid arthritis, prednisolon prescribed.And he bough his, but read about,that this is hormonal remedy and not interesting in curing, as interesting using an other cure. And maybe you cam share with us about these remedies, as for right use, and avoid side effects.

A hubby need to convince.

As any remedy having a side affect as with a cure . Hormonal glucocorticosteroids are preparations groups with a having natural hormones of adrenal cortex,and theirs synthetic subtitutes.

As adrenals are pair glands of inside secretions as over top poles finding a kidneys, and from this in calling.

And in medicine they are  using since long time a day, as effective very, anti inflamed, and immune suppresive/ immunedepressive /remedies,as stoping destroying a cartilage tissue in joints bone in rheumatoid arthritis.

As rheumatic pathologies are 200 and more, and a  most hard by display,course in a cure are autoimmune diseases as lupus, polymiositis, systemic vasculitis,rheumatoid arthritis. And a base inflammation therapy in these diseases are using By Rheumatologists as glucocrticosteroids, are high effective and fast effective remedies. And prednisolone for your hubby prescribed is right,try to talk with him and to convince in a needing using this remedy,why a long time to sick, if you can to cure faster...

And about theirs peculiarities,which you need to know in theirs using.And in depending from a long biologic effect these remedies are separating on a short effect as till 12 hours is natural as cortisone, middle effect is till 36 hours as prednisolone , methylprednisolone, triamcinolone and long till 48 hours as more are bethametasone, dexamethasone, and for readers are probably knew these remedies. Physiologic effects these remedies are in regulating for protein , carbohydrate, lipid metabolisms,and anti inflammation effect leading of lowering penetrating cappilares and immune suppressive to stop development a base cells as inborn immunity,which in infection or inflammation are producing an especial cells and molecules as aggravating a pathology. As right using these remedies and right dosages and methods for entering by a disease course,age a patient as faster improve his condition, and lowering risks for complications.

And a long, non control using these remedies are side effects displaying as a different level for hardness, and severity ,as a most often are syndrome cushingoid , weight rising here, face is rounding, bodies and tensions with stretch marks,acne. And course prolonging are displays hypertension, diabetes, osteoporosis, aseptic bones necrosis, muscle weakness, cataract, glaucoma, and high sensitiveness to infection.And what are about  avoid these side effects? Yes you can, if to use right rules.

As avoiding self curing, as self cure is self destroy. And rheumatologist prescribing remedies after a right diagnosis definition, with an process activity and other diseases in anamnesis.  And important here are dose selection and methods for entering theirs. And when in a cure lead a positive effect, doctor will low dosage till  minimal effective as a right controlling a disease course, conditions for systems, and organs. And usually they are using as pills , but if you are long time used till this are NSAID  thus theirs are cancel. and glucocorticosteroids using as are rectal suppositors ,rising dosage on 1.5 times. And thus you can damage your stomach and bowel. And in hard disease course,when are needing significant dosages,thus use a pulse therapy as intravenously entering a methylprednisolone and this therapy for 5 days lowering activity for process and not need a long slow lowering a dose, as this is happening in per oral method.  

As today are having lots of immune supressive effect remedies,and therefore we can to cure for a long time a high glucocorticosteroid dosages. And these are methotrexate, cyclophosphane, azatiopirine and gene engineering , biologic remedies , combination with which is gives fast effect without a side effects, but select theirs just your doctor need. As for adults anti inflamed therapy prescribing a low dosages and against lead are osteoporosis display, or osteonecrosis, and here need to use for preventing methods are remedies using as calcium and control level for vitamin D3.

And still a rule for intravenous entering in joint  are glucocorticosteroids,and this process doing if in joint having a liquid,which preliminary removing.And in infection procedure is cancel. And not enter remedies in dry joint. And injections using for one time in 3-4 months, and if liquid in joint filling faster,thus was been selected a base therapy. 

But somethings patients are self doing injections with these remedies,and this is avoiding doing, as in wrong using a fast metabolism of remedy happening with a less pronounced effect, and also you can enter infection.

As between doctor there is  a phrase  having ,as a most experience rheumatologist,thus are lowed dosages for glucocorticosteroids, he prescribes and less are side effects display he will cure.

By Balabanova, M.D, PH.D.