In my friend on 11 y ,old are yellowness eyes,weakness. Doctors said about a Gilbert s disease , what is it? Does she dangerous? Which cure is?
Its right calling his syndrome Gilbert s , is genetical peculiarity, and partially destroying bilirubin metabolism in blood, conditions not leading to destroying organism function and its lifelong complexes for symptoms-displays , and not looking by doctors as disease. First time his described on 1901 y. by French gastroenterologist Oposten Gilbert , are paid attention on the relatives groups patients with periodically jaundice, which not leading to global changes in organism. For 100 years syndrome is good learned and received a few calls as simple family cholemia, constitutional hyperbilirubinemia, not hemolytic family jaundice, idiopatical non conjugates hyperbilirubinemia , benign hyperbilirubinemia.
And you can be heard about bilirubin, but a not an all knows, that is a one from product for destroying are obsoleted are own date erythrocytes as red blood cells ,delivering from lungs is oxygen to organs and taking dioxide gas. Are two fractions of bilirubin having:
1. Not straight, non-conjugated in splitting erythrocytes getting , and in abundant quantities, travelling in organism, and accumulating in tissues, dying in yellow colour an creating intoxication.
Straight is conjugated , from a not straight getting in biochemical processes, easy secreting from liver in bowel, and free removing with urine and faeces, and not accumulating in organism. In Gilbert s syndrome in person having genetical defect, preventing a full transferring a bad not straight bilirubin in a good is straight. Meeting in 1-5 per of peoples are on the planet and first time displaying on the sex developing, displaying a without symptoms.And, its interesting geographical peculiarities spreading in Europeans are 2.5 percents of livers, in Asian 3-5 perc, Africans are 36 percents, and in males data genetical breaking meeting by different dates, from 3-4, till 8-10 times are often, that in males, and are third with Gilbert s enduring his without symptoms.
A main triad for signs a condition.
Yelowsness are eyes scleras different dye level, skin of face, rare are palms, feets, armpits holes, triangle nasolabial, mucus mouth cavity. As its an accumulating in blood toxic not straight bilirubin, and other displays having of intoxications, sleepiness, nausea, appetite lost.
Xanhtelasmas of eyelids are yellow plaques , different sizes by, over skin.
A periodically displaying symptoms as in certain condition, syndrome is giving about itself to know. And provokes are different stress factors, as destroying rhythm regime as starving, over eating, fatty , fat meal, alcohol, remedies, physical, psychical over tiredness, bacterial, virus infections, surgeries, injuries. And remember in ignoring provoked factors or not informed about this syndrome are ability to complicate an other conditions of organism, as a few diseases having jaundice is importance sign for Gilbert s syndrome.Thus, for confirming diagnosis is importance differential diagnosis are doing paediatrician/therapeutist, gastroenterologist with hepatologist. And with a common biochemical blood tests, coptorogram , as faeces test, urine common test, ultrasound for peritoneum organs and genetical tests.
It's a not disease, its genetical breaking of symptoms-complex and cure is nothing, just is preventing needing, what is to advice?
Avoiding over loading physical, psychical, stress, check for meal, low fats, alcohol, smoked, fried, alcohol, abiding starving, over eating, use diet nr 5 is your diet therapy. And for preventing gall stone with Gilbert having periodically used a cholagogue therapy are using agrimony, corn stigmas, artichoke, tansy, or remedies of them.
A bilirubin abundant remove with selected remedies as adsorbents, phenobarbitals, vitamins groups B, not B 3, AS HE IS RISING BILIRUBIN LEVEL IN BLOOD!
For destroying bilirubin in tissues using phototherapy by a light of blue lamps, but sun rays are avoiding!
In finding Gilbert s syndrome prognosis is favourable is hyperbilirubinemia having benign character and with using healthy life mode and for excepting complications for other organism condition! A life continuation is a not limited! And actual on today a moment:Syndrome Gilbert s is a not contraindication to vaccination !By N.Korsakova, pediatrist , dr by a high category.