Floors of integration.

 And it's not simple, so as mechanisms for recovering, stayed on different floors of organism, and them by uniting/integrating/, are groups of atoms, molecular machines, cells of tissues, combinations of organs and systems.

And on the last time attention for biochemistries and pathologists attention paid are molecular systems. Ion interactions, ferments and other biologic active substances are playing importance role in regulation of  physiological/homeostatical including/and pathologic processes.

 Study for next level are poly-molecular systems leading to was born a new power twig of modern science, calling a famous molecular biology. As her birthday tied with an opening in a  nucleus DNA ,that allowed studies biologic appearances on subcellular level and molecular. Managing by worked hypothesis, fixing and checking her hard experiments , scientists showing,  that between micro/ molecular/ and macrosystem organism a constantly having a calling and effecting back relations. And with theirs help are realizing self-regulation   not for healthy, but sicked organism. And in our institute for common pathology and pathologic physiology, was by experimentally evidences, that any adaptively organism reaction -are from the training to the physical loading/simple function/ till remembering/hard function/ are interacting  a thanks for activation for synthesis of nuclide acids and structure proteins. Abundant tension of ties between a neurohormonal system and into cellular synthesis, theirs over tension and breakdown/we are thought about a one this is of importance moments for period a pre-disease/taking importance role in development for chronic heart defect.

 Let s rise higher on the level for ultrastructure forming. He includes are visible in light microscope are cellular organelles, and to him belong containing ferments vacuoles-lysosomes . They are activity taking part in phagocytosis is organism protection from foreign agents is immunity, which involving to development allergy, tumors, allergy, injured shock. And its understanding, a which meaning having in lysosomes and futures theirs studying/ in period for pre-disease and disease for homeostasis keeping and returning to norm. These structures effecting in cells limits and in out of cellular spaces are on the floor of tissue systems, as in blood, fatty, muscle tissue. And checking for way future integration, we are selected levels for tissue functional elements as endocrine or breath system. All these are kaleidoscopic diversity, a uniting for integral organism. And organism, like iceberg, a big of part hide underwater. All thin biochemical reactions displaying underwater in molecules milliards, cells and theirs systems. So as in deep beginning any disease, with first destroys , characterizing for pre disease condition. Mechanisms for homeostasis saving  as self suppressing for many disturbances, appearing  on the low levels of organism, lead not till our sense. And after this, as chain reaction for deviation from norm catching are extensive regions of organism, transforming in generalizing/spillover/ pathologic process, we are feeling bad beginning and to the doctor visiting.