Membranes.

 Membranes

Life is the perpetual movement of fluids between cells and within cells. Stopping this movement leads to death. Partial slowing down of the movement of fluids in some organ causes partial breakdown. The general slowdown of extra- and intracellular fluids in the body causes disease. The exchange is carried out mainly through capillaries and membranes.

In the section on capillaries, you will find numerous examples and convincing illustrations. Before examining each patient, you need to remember this phenomenon.

Changes in capillary membranes really play an important role in the development of the disease:

1) lungs (all pulmonary diseases, including devastating tuberculosis);

2) digestive organs (peptic ulcer, liver and gallbladder diseases);

3) kidney (pyelitis, nephritis, hydropielonephrosis, lipoid nephrosis);

4) blood vessels (arteritis, phlebitis, lymphangitis, elephantiasis);

5) skin (eczema, nettle fever, pemphigus);

6) the heart and its circulation (valvulitis, endocarditis, myocardial infarction, pericarditis, etc.);

7) the nervous system (cerebral edema, encephalitis, epilepsy, myelopathy);

8) the organ of vision (glaucoma, cataracts, etc.).

In all cases, it is necessary first of all to restore the permeability of the membranes. Never forget about capillary endothelial membranes and parenchymal cell membranes.

Membranes can thicken, become impermeable, the distance between cell membranes can be increased due to shrinkage of endothelial cells. This is the so-called "hyperporia". The distance between the membranes can also decrease, then we get "hypoporia". Cell membranes can be destroyed - cell decay or death occurs.

One should always think about the accumulation and excretion of metabolites; this is again the question of filtering, scattering, osmotic membranes. It is necessary to forget the labels of individual diseases and, above all, restore the energy balance: respiration, blood circulation, food assimilation and excretion. You should always keep your brain membranes fresh, moist, and permeable.

If you strictly adhere to book labels, if you limit yourself to the usual classification, then you will be like a dried entomologist who collects dead or half-dead insects.

To become a specialist in membranology means to abandon all medical specializations and become a true sower of life and health.

Anti-gravity movement and "micro-explosions"

The explosive shell in the sleeve weighs 500 kg - 1/2 tons. When released into the air, it has a force of 25,000 tons and covers a distance of 20 km, overcoming the force of gravity. The energy of the explosion, expressed as the mass of inert matter, overcomes gravity.

The process of expectoration, sputum ascent, accumulation of droplets of mucus and pus from the depths of the alveoli, bronchioles, in other words, the movement against gravity could be explained as the result of countless enzymatic explosions in the cytoplasm of endothelial cells of alveoli, epithelial cells of the mucous membrane of bronchioles and bronchi.

The ascent of groundwater to the top of the plant, this stream, which begins in the roots, sucks in groundwater and transports it 40, 50 or 60 m upward, could also be explained by enzymatic microexplosions occurring in the cytoplasm of plant cells of roots and cells covering the tubules - real vessels in the depths of tree trunks. Accurate calculation of regulated enzymatic explosions is the main source of vital and psychic energy.

To explain this phenomenon, you need to compare it with what happens in a powder store when it is poorly ventilated (self-ignition). Lack of ventilation, local hypoxemia can generally cause inflammation in cells and tissues. Inflammation of the lungs is an overwhelming example. In proteins of the cytoplasm and extracellular fluid, we find acetone, and in catabolic reactions - etheric and alcoholic substances. Thus, sudden outbreaks of acute infectious diseases and acute dermatitis can be explained.

An exclusively microbiological view is too naive and too simplistic. It is more correct to assume that enzymatic explosions are the normal course of life. The same enzymatic explosions, but irregular, weakened, irregular, become the primary cause of chronic degeneration.The explosion of nitroglycerin is possible only if the explosive is of a gelatinous nature. To prepare nitroglycerin, you need gelatin and a very strong oxidizing agent (jelly + sulfuric acid).

The cytoplasm is a jelly constantly irrigated with oxygen brought in from the outside and released by an enzymatic reaction. The cytoplasm contains sulfur, which combines substances and creates the conditions necessary for cellular microexplosions. Enzymatic microexplosions continuously occur in the cellular cytoplasm; in countless microdots of cytoplasmic jelly, these explosions represent the energetic sources of life.

Countless microexplosions in each cell extend over a surface of 200 hectares (the surface of the cytoplasm of the entire human body). At every point, this wonderfully organized and well-confined explosion is weak and harmless, but the sheer number of micro-explosions provides a constant flow of life force.

The fever can be attributed to an increase in enzymatic microexplosions. Fatigue, perhaps, is a consequence of a decrease in the number and intensity of enzymatic microexplosions. Enzymatic pathophysiology is a new era in biology and pathology.

The hypothesis of enzymatic microexplosions was first put forward by the famous botanist Soueges (1949, 1954). In his wonderful books "The Life of Plants" and "Kinematics of Life" he wrote that the egg is an exemplary cell, perfect and omnipotent, possessing all the properties, but without bringing anything to the end. This cell, containing all hereditary potencies, but in which they have not yet learned to distinguish any particle of this inheritance, necessarily has a special physicochemical organization. It is very well compared to a powerful capacitor, all parts of which, even the smallest ones, are in an unusually close connection.

This capacitor can act as an explosive or explosive complex. Its action would correspond to a series of different explosions. Explosive reactions occur in the depths of colloidal micelles between unstable, unstable giant molecules of which they are composed. The smallest chemical and physical factors can affect these molecules, deeply change them, cause isomerization or the formation of ethers, etc. They are the reason for the emergence of a new state of equilibrium.

Here is a quote from the excellent work of the famous physiologist Shoshar: “The release of the chemical link must be done very quickly. If we are talking about the synthesis in the system of nervous stimulation, we are talking about the explosion of a preexisting phosphorus molecule ”(Chauchard, 1943, p, 111).

Any disease is a quantitative process characterized by an excessive number of destroyed cells, whether blood or parenchymal. For the disease, a large amount of toxic proteins is always typical, which arise as a result of the destruction of microbes, sacrificed phagocytes or the decay of tissue cytoplasm that has experienced traumatic, chemical, heat or microbial shock.

To eliminate an attack of the disease, you must first of all open the excretory tract: cleanse the intestines, lungs, kidneys, skin, liver; it is necessary to immediately open spasmodically and atonically closed capillaries; then the movement of plasma will increase, the plasma will be freed from toxins and will accept antibodies, enzymes, diastases, oxygen, glucose and nutrients from the body's reserve. The body is cleansed and toxic substances are removed.

If the therapy remains strictly medication, the body will be freed from some microbes, but there will be room for other microbes. Toxic proteins will remain in the body, affecting various areas of the body. Acute health hazards may disappear, but are replaced by chronic diseases that are atypical and difficult to diagnose.

Microexplosions and radioactivity

The microexplosion hypothesis was confirmed in 1960 at the National Nuclear Physics Laboratory in the United States. A message from the Atomic Energy Commission was relayed, and this message was repeated by several American scientific observers.

A completely isolated cell with an area of ​​1.8 m was built. For the best isolation of the chamber from the penetration of atmospheric radioactivity, 60 tons of steel were used with a wall thickness of 20 cm.

The subject, a healthy person, stripped of clothes, barefoot, wrapped in a special cloth, lies on a couch. Near the couch is a crystal of potassium iodide (its diameter is 20 cm), enclosed in a steel cassette. A potassium iodide crystal has the ability to glow every time a radioactive particle hits it. Registration of light waves caused by radioactive particles is carried out using a photomultiplier mechanism on a special installation. On a screen outside the camera and connected to the counters, physicists record the number of infinitely tiny radioactive particles sent out by the human body. These experiments were carried out repeatedly on a large number of subjects.

 Thus, it has been proven that billions of micro-explosions occur in our body every minute. Hence, new problems arise. First of all, it would be necessary to try to establish where the warehouse of biological microbombs is located. It is known that cell membranes are the site of activity of enzymes located on the cell surface. Their explosive activity is a biological phenomenon. But there is another, pre-explosive system - a myriad of microbomb stores attached to mitochondria. Each mitochondrion is an extremely important metabolic intracellular apparatus. Their number is many times greater than the number of cells in the human body.

Mitochondria of very thin formations in granules or rods are located around the cell nucleus. They have enzymatic explosive properties. Mitochondria are the main, if not the only focus of oxidation processes in the cell, i.e. cell respiration occurs with the help of mitochondria. This is a fundamental fact.

The supposed effects of gradual explosions of radioactive microbombs in our body allow us to put forward some hypotheses that are quite plausible within the limits of available observations.

1) Radioactivity in the human body "tamed", detoxifying, specially oriented, well adapted to the needs of life, is the primary source of vital energy.

2) Life-giving animal radioactivity is exposed from destructive radioactivity, killing quantitatively and qualitatively. Nuclear physics is designed to measure the rhythm of atomic microexplosions in every part of the human body, in every organ, in every tissue, in every cell.

3) Teams of biologists with very basic knowledge in the field of nuclear physics must cooperate with physicists.

Huge horizons are opening up for biology, physiology and pathology. The birth of nerve currents, their transformation into elements of thought, the cries of newborns, calm or restless sleep, hunger, thirst, vegetative and mental phenomena, the first efforts to catch, grab a walk, the birth of curiosity about things around, a sense of security in the arms of the mother, each enrichment of the tactile, visual, acoustic and gustatory sensations should be accompanied by a modification of the intensity and rhythm of microexplosions in different areas of the body.

Already now it is possible to measure the quantity, register various rhythms of microexplosions and determine the interdependence between primitive mental processes and modifications of the rhythm and intensity of microexplosions. One could also measure the correlations between the first babble, the first spoken words, and microexplosions. Physiologists and educators will have to work together with physicists.

Biochemistry and biophysics

The name of the first science does not in the least correspond to the subject contained in this section of chemistry. Biochemistry, in fact, means: the chemistry of life, the chemistry of vital phenomena. However, neither chemists nor physiologists are able to provide any explanation for life. Biochemists do not even try to raise this basic question. Biochemistry describes only the substances found in the animal organism; she examines the changes in these substances in the body. But biochemists cannot get real biochemical reactions in their laboratories.

Chemical transformations in the body occur with extraordinary rapidity or extraordinary slowness (closure of wounds, scarring process, accumulation of phosphocalcium reserves, restoration of cytoplasm in damaged cells); all these reactions in the body decompose solutes at a temperature of 38-39 ° C, while in a biochemical laboratory a much higher temperature would be needed.

In the human body, countless enzymes, coenzymes are instantly mobilized for each hydrolysis or synthesis reaction; there is no organ, tissue, cell that would not receive a signal; there is no amount of energy that does not change its energy potential. The dog swallows a piece of meat. The sight of the meat excites her retina and her brain; the salivary glands secrete saliva, which causes contractions of the esophagus, gastric motility, changes in the release of carbon dioxide and various juices. Everything changes in the body. Anything and everywhere.

Biochemical tests, which occupy a dominant place in physiopathology, are not able to explain the mechanism or main factors of painful changes. It is impossible to explain the chemical reaction in the cells, one can only observe the presence of the product and one can only distinguish between the main substance and the final product. Intermediate reactions are not observable.

Cytochemistry (or histochemistry) is as old as cytology itself. To observe chemical reactions in droplets several thousandths of a millimeter in size, you must first make the substance immobile without changing the cellular structure, then you need to find a color reaction to color small grains or choose a characteristic solvent to distinguish the grains from other components of the cell; from all this it is clear that cytochemistry is going through the period of its childhood. It indicates to us the presence of a substance in significant quantities, but does not reveal the exact place where these substances were formed. When the movement of a cell caused by exposure to a chemical is observed, one speaks of chemotaxis. When the effect on a cell of a physical factor, for example, gravity, is observed, one speaks of barotropism. When the effect of light on cellular substances is observed, one speaks of phototropism, or phototaxis. They are content with this, but the biochemical laboratory is not a circus, not a cabaret.

When chemists have the courage to say “we know very little,” and in some cases, “we know nothing,” then the flawed habit of inventing useless terms, assigning identifying marks to phantoms will disappear. And, perhaps, they will begin to think, think, select facts, instead of collecting fragments of chemical knowledge without a plan, without a guiding idea.

The smallest branches of the pulmonary artery have a fairly powerful muscle layer and are able to tolerate significant changes in caliber. This caliber can be reduced by three times. A threefold reduction in caliber means a 9-fold reduction in cross-sectional area and an approximately 27-fold increase in blood flow resistance (Policard, 1Q55).

But both in normal physiology and in pathology, it is said about observations over the zones where the surface of the vessels withstands the resistance of significant blood pressure, without causing serious disorders. This means that the resistance of the walls of blood vessels and blood cells to mechanical or physical phenomena is enormous. On the other hand, every change in pH in body fluids is very limited. Knowing this, you will understand that our applications of physical influences (heat, cold) represent a wide field of activity, much broader and better controllable than our chemical recipes, which are very limited, because the range of biochemical changes associated with life is extremely small. ...

The speed of biochemical reactions (12 reactions to decompose a glucose molecule in 1/10 s), the inability to influence the enzymatic and cellular world require a little modesty and reflection from our conscience when evaluating the beneficialness of one pharmacology.

Make an arithmetic calculation and you will find that balneotherapy (heating pads, hot wraps, baths) is more effective than all pharmacology. Balneotherapy, well performed, never poses a danger of growing resistant microbes, it does not narcotize, it does not poison.

General eurhythmia

There are cases, and they are not uncommon, when the death of a patient cannot be explained either by the development of painful phenomena, or by the insufficiency of the most important types of body activity (respiration, blood circulation, excretion), or by serious near-death complications. There remains a plausible hypothesis: this is a violation of synchronous eurhythmia.

In a healthy person, the number of breaths per minute should fluctuate between 26 and 20, the heart should contract from 72 to 80 times per minute and the kidney should filter a certain amount of urine. Unloading oxygen on the way: lung, blood, myoglobin, oxygen, lactic acid, muscle fiber - occurs very rhythmically: 300 times per minute.

The quantitative correspondence between the rhythm of respiration - 18 per minute, contractions of the heart - 72 times per minute and the rhythm of myoglobin dissociation - 300 per minute is worthy of surprise. The number of breaths per minute (R): 18 multiplied by 4 gives the number of heartbeats (C): 72 per minute; the number of systoles - 72, 75, multiplied by 4, gives the number of oxygen return in the skeletal muscle, delivered by myoglobin (M), 75x4 = 300. This proportion can be represented as an algebraic formula for synchronous rhythm: Rx4 = C, Cx4 = M.

 It takes one breath to deliver enough oxygen for four myocardial contractions. It takes one contraction of the myocardium to deliver the volume of oxygen for the four contractions of the striated and smooth muscle fibers. The synchronized rhythm of the number of breaths, the number of systoles and the number of oxygen deliveries to the muscle fiber is obvious.

If oxygen were simply dissolved in the blood and not combined with red blood cells, the heart would have to beat 40 times faster than it does at present in order to ensure tissue respiration.

Proponents of intravenous injections, doctors who have injected various substances directly into the blood for 40 years, often very poisonous, do not realize what confusion they cause in the composition of the blood, how much blood cells are destroyed by these injections, how many shocks occur in the plasma, what inflammatory processes and phenomena of degeneration are caused by them in the deep endothelium of repeatedly damaged arteries and veins. This tragic delusion has been going on for almost half a century. The number of phlebitis, thrombosis, embolism, arteritis has been continuously increasing since the introduction of intravenous injections.

Only one indignant voice, the physiologist Back, 1956, rose up against this professional and moral frivolity.

The study of the rhythm of various physiological functions could lead to very interesting discoveries. The rhythm of peristalsis of a full and empty stomach, the rhythm of the secretion of gastric and intestinal juice, the rhythm of the secretion of hepatic and gallbladder bile and the rhythm of urine output, the duration and rhythm of some reactions of catabolism and anabolism could greatly expand our knowledge of synchronized eurhythmia.

Chapter 3. Between health and disease

Fatigue

Fatigue is a phenomenon common to the entire animal kingdom. There are various degrees of fatigue: physiologists know the fatigue of the "amoeboid" movements of leukocytes, ciliated cilia (epithelium of the bronchi, bronchioles, etc.) and fatigue of muscle fibers.

Fatigue in a healthy normal person is a decrease in the functional capacity of organs caused by overwork and accompanied by a characteristic feeling of malaise.

Movement due to a change in turgor in Mimosa pudica stops after some time if it is subjected to too often repeated mechanical stimuli. A certain period of rest is required to restore the plant's mobility. The striated muscle fatigues faster than the smooth muscle. Muscle fatigue is characterized by a decrease or loss of the ability to contract. In an attempt to establish "optimal" conditions for work and rest, Maggiora observed that by bending the middle finger under the control of the ergograph every 10 s, it was never possible to tire him out; therefore, a 10-second rest between contractions is sufficient for a full recovery.

Rapid burning of glycogen, a rise in temperature, and increased sweating cause muscle fatigue. In the open air at cool temperatures, muscle fatigue occurs later than in a room with a high or even moderate temperature and a suffocating atmosphere.

Fatigue causes a huge consumption of oxygen and glycogen, excess lactic acid, the accumulation of amino acids and other protein substances in the blood. The liver, poor in oxygen and glycogen, cannot break down protein particles into harmless metabolites. Fatigue of a nerve is recognized by a decrease or loss of conductivity: in the organs of vision - by a decrease in susceptibility to light, in the organ of hearing - by a loss or decrease in susceptibility to sound.

Along with physical fatigue, heat fatigue and fatigue caused by chemical changes should be noted. Fatigue is distributed in a certain way. The most important organs (nerve centers) are better protected from fatigue due to a special tissue hierarchy. This suggests a close juxtaposition of fatigue with hunger. It is known that under the influence of depletion, body tissues lose mass so that the brain can feed on organic reserves. The brain that dies last (ultimum moriens) is also the most active (ultimum movens).

Fatigue builds up in the body progressively. Oxidation products during muscle contractions are released into the bloodstream and chemically affect the sensitive nerve endings contained in the muscles. Fatigue can be reduced by exercise, which makes the body more resistant to fatigue. Engelmann and Verworn succeeded in accustoming various unicellular organisms to concentrated salt solutions, which initially caused them a pronounced arousal. You can get used to weak poisonous solutions, to high temperatures, to intense light. It is only necessary to apply small doses and gradually increase them. This is the secret of physical and mental training.

With muscle fatigue, the muscle absorbs nutrients and is poisoned by their waste products, which cannot be excreted or neutralized quickly enough. Every fatigue is poisoning. The increased release of metabolites leads to the elimination of poisoning.

Fatigue reduces the body's ability to rid itself of ptomains. It can be argued that ptomains become dangerous only if the body is tired. They can be called fatigue toxins. Fatigue poisons, the result of the accumulation of non-neutralized ptomains, cause a predisposition to infectious or degenerative diseases.

If we agree with this hypothesis of "fatigue toxins" (and it is difficult to disagree with it), as with the predominant factor in the loss of immunity, it is necessary to revise the classical theory of immunity. Complete sterilization of the body - Ehrlich's dream - was and remains a utopia. Without colibacilli in a normally functioning intestine, the last phase of digestion would not be possible.

Fatigue does not completely burn out the nutrients. Since work is associated with the consumption of oxygen, it is useless to treat fatigue with increased nutrition. Strenuous muscular work very often causes a slight fever, febrile weakness (lumberjack fever, heat strokes in soldiers after long marches).

Overstrain in military exercises and in sports. At the beginning of military training, there is always a decrease in the body weight of the soldiers. Changes in living conditions cause a decrease in organic reserves and an increase in metabolism. After 3 months of exercise, the weight increases again by 3-4 kg. This increase is mainly due to hypertrophy of the leg muscles. The muscles in the arms do not change, and the respiratory muscles may even shrink. This means that we can state an increased blood supply to the capillary network of the respiratory muscles, which require an excess of oxygen, while a reduced blood supply to the respiratory muscles leads to their depletion of oxygen and causes hypertrophy. Mosso has amassed ample evidence that smaller muscles can do the same amount of work and perform even better than larger muscles. The extraordinary speed and endurance of the Ethiopians during the campaigns are well known; but it is the Ethiopians and the Arabs who have very slender legs. Mosso observed in the Alps famous conductors with underdeveloped leg muscles.

Muscle work does not increase their volume until it becomes excessive for them. The respiratory muscles, diaphragm, and intercostal muscles do not increase in volume, although they remain active throughout life. The heart muscle does not hypertrophy under normal conditions. It only increases with valve disease or overwork. Hypertrophy of a muscle does not increase its ability to perform large mechanical work over time. Gymnastics teachers are the least resilient in the field and the most tired of military life.

Emotional fatigue. Symptoms of emotional fatigue: sweating, dilated pupils, increased release of adrenaline, thyroxine, palpitations, respiratory arrhythmia, spastic state of the intestinal tract, diarrhea, polyuria, in a word, all oxidation, nutrition and excretion disorders.

Acoustic fatigue. The use of ultrasound sometimes causes bleeding in the meninges and in the tissues of the brain. This is the maximum harm caused by the irritation of the acoustic centers. It can be assumed that the stimulation of these centers or other parts of the central nervous system by waves of a lower frequency than ultrasound can cause much smaller changes. But they still require attention, because these irritations are longer, although less intense.

Day, night, earth, water, air deafening noise causes an increase in nervousness, weakening of attention. In the canton of Grisons (Switzerland), the movement of cars was for some time prohibited, during this period the level of academic performance of schoolchildren was higher than in all other cantons. A minimum of rest is necessary to collect at least a few meager thoughts. Fatigue of the brain corresponds to a decrease in the blood supply to nerve cells; an unexplored mystery of the brain lies at the heart of it.

Different types of fatigue inevitably cause different diseases. This is an unshakable law. It is very important to cure granuloma or tuberculous meningitis with streptomycin, but if fatigue is not eliminated, tuberculosis or other serious illness will return.

The pathogenic role of fatigue. Carrier has shown the importance of fatigue in most diseases. Reudon has published a dissertation on overwork fever. We can also mention the convincing works of Lagrange, Leyden, Robin, Roger, Marfan.

Excessive temperatures contribute to fatigue. Fatigue occurs more quickly when the atmospheric pressure drops and the relative humidity rises. According to Mosso, fatigue fever can be compared with traumatic fever (absorption of metabolic products, fever after long walks in recovering tuberculosis patients). Axel Key (Key) drew attention to the almost constant increase in the number of sick children when moving from class to class in a Stockholm school: first grade 17%, second - 30%, fourth - 40%. The increase in myopia in relation to the duration of classes is well known to ophthalmologists. Inconvenient distribution of lessons, uninteresting and unhelpful teaching can have a devastating effect on the mental abilities of children.

The cause of fatigue is the accumulation of metabolic products in the muscles during the conversion of chemical energy into mechanical and thermal energy. You can induce fatigue symptoms in a muscle at rest by injecting an aqueous extract from the fatigued muscle into its arteries; on the other hand, the effects of fatigue can be eliminated by "rinsing" the arteries of the tired muscle with isotonic saline solution, which removes metabolites, increasing the irrigation of the muscle, opening closed capillaries in it. Balneotherapy of capillaries eliminates fatigue poisons. In a cat, the pH of a tired muscle drops to almost 6.2. In fresh muscle, the pH is 7.0-7.1. Blood is a conductor of animal heat, the “human Gulf Stream”. Muscle is a heat motor In the resting muscle, only one-twentieth of the capillaries are dilated; in a working muscle, all or almost all of the capillaries are dilated. There is not a single ailment, not a single illness without prior fatigue.

Humoral fatigue syndrome

Every fatigue - muscle, emotional - generates changes in the composition of blood and urine. Some authors, examining the blood of people after fatigue, note an increase in the number of red blood cells, other researchers, on the contrary, a decrease. In cases of moderate fatigue, an intensification of erythropoids (neoformation of erythrocytes) and the appearance of reticulocytes are noted. When fatigue becomes excessive, the number of red blood cells decreases, inhibition of the activity of the braids of that brain, a plant that continuously produces red blood cells, is noted. Globular anemia appears. The relationship between excessive fatigue and hypochromic anemia is becoming clear.

On the other hand, thickening of the blood, an increase in hemiconcentration during moderate short-term fatigue, could be considered as the dominant factor in thrombogenesis. Hemoglobin either increases or decreases, depending on the change in plasma volume.

Fatigue also provokes an increase in lymphocytes and polynuclear leukocytes. Blood clotting is accelerated, and the bleeding time is closely related to the degree of fatigue; hemoconcengracin is accompanied by an increase in the number of platelets and fibrinogen.

Comparing the shape of red blood cells, their fragility, thinking about the increase in the number of leukocytes and lymphocytes caused by fatigue, it can be argued that every fatigue, even mild, is accompanied by temporary anemia and microleukemia. If fatigue lasts too long, if it becomes excessive, it can in some cases be the etiological factor behind Birmer's anemia, leukemia, bone marrow fatigue and blood clots.

The hierly therapeutic gesture is the organization of a long rest. Already 95 years ago, they understood the need for rest for patients affected by progressive pulmonary tuberculosis. It is also necessary to organize the elimination of countless corpses of erythrocytes, leukocytes and lymphocytes through the urinary tract. It is necessary to stop the antiphysiological use of radioactive substances, which indiscriminately ruthlessly kill erythrocytes and the patients themselves. No one wants to think about the fact that by increasing the number of dead red blood cells, they clog the excretory pathways and increase protein intoxication.

Fatigue is accompanied by acidosis, the release of adrenaline, which stimulates the contraction of the spleen, which drives large lymphocytes into the bloodstream. The increased formation of lactic acid by muscles provokes disaggregation of liver glycogen, a decrease in the glucose reserve and the appearance of hypoglycemia.

The harmful effects of hypoglycemia on the nervous system are well known. How many hypoglycemic patients are treated as epileptics due to morning convulsions. 4-5 lumps of sugar on awakening cure these "unfortunate epileptics". Hypoglycemia also causes acetonemia, which regresses after sugar intake; the role of carbohydrate metabolites in the combustion of acetone is known.

Hemoconcentration, dehydration of blood plasma, increased fragility of erythrocytes, increased potassium, decreased glycemia, leukocytosis, increased platelet count, a tendency to form blood clots - all this characterizes the consequences of fatigue as a pre-painful condition that could give rise to a real disease if rest did not relieve blood fatigue, fatigue erythrocytes, leukocytes, dangerous fatigue of the bone marrow and spleen - the cradle and graveyard of red blood cells.

Muscle fatigue, emotional, digestive, visual, acoustic, gives rise to humoral, tissue and cellular fatigue, Most of all, perturbation in the blood is reflected in the composition of urine. There is a decrease in urine output during exercise. Fatigue albuminuria occurs in more than half of fatigued individuals, especially those who have suffered prolonged muscle tension.

It has been noticed that albuminuria of fatigue is accompanied by the appearance of granular casts. This is the pathogenic bridge between fatigue and nephritis, which can become chronic. Therefore, it is necessary to do urinalysis after grueling walking in soldiers and athletes.

Prof. Tayeau believed that humoral fatigue syndrome is rarely complete: some forms of fatigue elude its biological identification. The ideal would be to have an analysis that, in addition to all the elements, would indicate the degree of suffering. This analysis should serve as a distress signal by which an immediate cessation of work should be ordered.

Now, this distress signal exists. This is a dermographic reaction. With the back of the percussion hammer, lightly stroke the patient's back. If, instead of a pink or thin red line (a sign of contraction of skin capillaries), you find a white line that remains white until it disappears, this will indicate a lack of capillary reaction. And when you detect the presence of this white line, your diagnosis of capillary inertness has already been established. At the same time, the viability of the examined patient is minimal. Therefore, the cessation of long-term work should be prescribed.

Real preventive medicine should avoid vaccinations against infections. Real preventive medicine should promote the organization of such primary, secondary and higher education, in which the memory of children and young people will not be loaded, their studies will revive, programs will be reduced, stimulating intellectual curiosity in students. The school doctor must become a respected member of the teacher's board to prohibit overloading recovering students. The modern school produces physically tired subjects, intellectually indifferent, devoid of a sense of citizenship, a sense of responsibility.

The statesmen responsible for the future nations must understand that the future of each nation depends primarily on the value of the growing capital of the human mass, the only source of material and cultural enrichment. Everything possible must be done to reduce the degree and duration of fatigue in every workshop, at every construction site, at every institution, at every administrative point.

Occupational medicine, which so far only registers incidents, accidents at work, should be presented to the plant management as a sufficiently authoritative person to organize such working conditions that will help avoid fatigue, which is incompatible with the preservation of working capacity.

The problem of older people who are removed from active life at the age of 60 must be reconsidered. The number of inactive old people will decrease, they will work up to 70-80 years. The state budget will be reduced and life expectancy will increase. The number of infectious diseases will decrease, the number of degenerative changes in organs will drop to a minimum, the pharmaceutical industry will lose 30% of consumers, drug diseases will disappear, the madness of politicians seeking to conquer the whole world will disappear.